State Street becomes substantial holder in Mesoblast Limited

State Street Corporation and its subsidiaries became a substantial holder in Mesoblast Limited on December 5, 2025, with a total voting power of 5.04%. This stake represents 64,604,716 ordinary shares in the company.

The relevant interest is held through various entities, including State Street Global Advisors Europe Limited, State Street Bank and Trust Company, State Street Global Advisors Trust Company, SSGA Funds Management, Inc., State Street Global Advisors Limited, and State Street Global Advisors, Australia, Limited. These entities hold interests as investment managers or trustees, and in some cases, through securities lending agreements as both lender and borrower.

The acquisitions of Mesoblast Limited securities occurred over several months, from August 2025 to December 2025. Transactions involved both cash and non-cash considerations, with numerous daily changes in holdings. For example, State Street Bank and Trust Company recorded various acquisitions and disposals, including a large acquisition of 1,846,364 ordinary shares on December 5, 2025.